姓名：宋秋玲

 职称：教授，博士生导师

 学历：博士研究生

 专业：有机化学

 邮箱：qsong@fzu.edu.cn

 研究方向：有机硼化学，有机氟化学，自由基化学

 课题组主页：https://www.x-mol.com/groups/song_qiuling

工作经历：

2023.3-至今，betway必威西汉姆联官网，教授

2012.11-2023.2，华侨大学，教授

2012.1-2012.11，华侨大学，副教授

2007.1-2011.12，美国制药公司，研究员/项目主管

教育背景：

1994.09-1998.06，郑州大学，化学系，学士

1998.09-2001.06，北京大学，化学与分子工程学院，硕士（保送） (导师：席振峰 教授）

2002.09-2006.12，美国普林斯顿大学，化学系，博士 （导师：Prof. Robert A Pascal）

科研简介:

主要从事有机硼化学、有机氟化学、自由基化学方面的研究。目前已在Acc. Chem. Res.、Chem. Soc. Rev.、Nat. Synth.、Chem、ACS. Cent. Sci.、J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、Nat. Commun.、CCS Chem.、Sci. China Chem.等学术期刊论文发表论文一百余篇，详见课题组主页https://www.x-mol.com/groups/song_qiuling。

代表论文:

45. N -Heterocycle-Editing to Access Fused-BN-Heterocycles via Ring-Opening/C-H Borylation/Reductive C-B Bond Formation”, Xu Zhang, Wanlan Su, Huosheng Guo, Pengyuan Fang, Kai Yang* and Qiuling Song*, Angew. Chem. Int. Ed. 2024, 63, e202318613.

44. “Ni-catalysed assembly of axially chiral alkenes from alkynyl tetracoordinate borons via 1,3-metallate shift” Xingxing Ma, Mengwei Tan, Luo Li, Zihao Zhong, Puhui Li, Jinchao Liang and Qiuling Song * Nat. Chem. 2024, 16, 42-53.pages42–53,

43. “Palladium-Catalyzed Difluorocarbene Transfer Enabled Divergent Synthesis of γ-Butenolides and Ynones from Iodobenzene and Terminal Alkynes”, Heyun Sheng, Zhiwei Chen, and Qiuling Song*, J. Am. Chem.Soc. 2024, 146, 1722–1731.

42. "Enantio- and regioselective [2 + 2 + 2] cycloaddition of BN-diynes for construction of C-B axial chirality”,Hao Wang, Bolin Qiao, Jide Zhu, Huosheng Guo, Zhen Zhang, Kai Yang*, Shi-Jun Li, Yu Lan*, Qiuling Song*, Chem 2023, 10, 317–329.

41. “Palladium-Catalyzed Atroposelective Kinetic C−H Olefination and Allylation for the Synthesis of C-B Axial Chirality”, Jie Xu, Weihua Qiu, Xu Zhang, Zhihan Wu, Zhen Zhang, Kai Yang, Qiuling Song*, Angew. Chem. Int. Ed. 2023, 62, e202313388

40. “Decarboxylation of β-boryl NHPI esters enables radical 1,2-boron shift for the assembly of versatile organoborons”, Yu Guo, Xiaosha Wang, Chengbo Li, Jianke Su, Jian Xu* and Qiuling Song*, Nat. Commun. 2023, 14, 5693.

39. “Transition-metal-free C(sp2)–C(sp3) cross-coupling of α-(pseudo)halo aliphatic ketones with boronic acids via a 1,4-metallate shift”, Xue Li, Haohua Chen, Hao Wang, Qiaohui Zhang, Heyun Sheng, Yu Lan* and Qiuling Song*, Nat. Synth. 2023, 2, 1211-1221.

38. “Construction of C-B axial chirality via dynamic kinetic asymmetric cross-coupling mediated by tetracoordinate boron”, Kai Yang, Yanfei Mao, Zhihan Zhang, Jie Xu, Hao Wang, Yong He, Peiyuan Yu* and Qiuling Song*, Nat. Commun. 2023, 14, 4438.

37. “Cu(I)-Catalyzed Highly Diastereo- and Enantioselective Constructions of Boron/Carbon Vicinal Stereogenic Centers via Insertion Reaction”, Guan Zhang, Xinping Cai, Junyi Jia, Bofan Feng, Kai Yang, and Qiuling Song*, ACS Catal. 2023, 13, 9502-9508.

36. “Unconventional Transformations of Difluorocarbene with Amines and Ethers”, Xingxing Ma, Jianke Su and Qiuling Song*, Acc. Chem. Res. 2023, 56, 592-607.

35. “Modular Assembly of Versatile Tetrasubstituted Alkenyl Monohalides from Alkynyl Tetracoordinate Borons”, Xingxing Ma, Luo Li, Mengwei Tan, Zihao Zhong, Jinchao Liang, Puhui Li and Qiuling Song*, Chem, 2023, doi: 10.1016/j.chempr.2023.01.005.

34. “Construction of Axially Chiral Alkenylboronates via Cu/Pd Dual Catalysis-Promoted Atroposelective Arylboration of Alkynes”, Wangyang Li, Shanglin Chen, Jinhui Xie, Zhenwei Fan, Kai Yang and Qiuling Song*, Nat. Synth. 2023, 2, 140-151.

33. “Deaminative Arylation or Alkenylation of Aliphatic Tertiary Amines with Aryl or Alkenylboronic Acids via Nitrogen Ylides”, Jianke Su, Chengbo Li, Xinyuan Hu, Yu Guo and Qiuling Song*, Angew. Chem. Int. Ed. 2022, 61, doi: 10.1002/anie.202212740.

32. “Enantioselective Copper-Catalyzed sp2/sp3 Diborylation of 1,1-Chloro-Trifluoromethyl– 2-alkenes”, Zhenwei Fan, Mingxing Ye, Yahao Wang, Jian Qiu, Wangyang Li, Xingxing Ma, Kai Yang and Qiuling Song*, ACS Cent. Sci. 2022, 8, doi: 10.1021/acscentsci.2c00339.

31. “Enantioselective Cu-catalyzed double hydroboration of alkynes to access chiral gem-diborylalkanes”, Shengnan Jin, Jinxia Li, Kang Liu, Wei-Yi Ding, Shuai Wang, Xiujuan Huang, Xue Li, Peiyuan Yu and Qiuling Song*, Nat. Commun. 2022, 13, 3524-3536.

30. “Construction of boron-stereogenic compounds via enantioselective Cu-catalyzed desymmetric B–H bond insertion reaction”,  Guan Zhang, Zhihan Zhang, Mengyuan Hou, Xinping Cai, Kai Yang, Peiyuan Yu* and Qiuling Song*, Nat. Commun. 2022, 13, 2624-2635.

29. “Photo-induced trifunctionalization of bromostyrenes via remote radical migration reactions of tetracoordinate boron species”, Chaokun Li, Shangteng Liao, Shanglin Chen, Nan Chen, Feng Zhang, Kai Yang and Qiuling Song*, Nat. Commun. 2022, 13, 1748-1760.

28. “Enantioselective Cobalt-Catalyzed Cascade Hydrosilylation and Hydroboration of Alkynes to Access Enantioenriched 1,1-Silylboryl Alkanes”, Shengnan Jin, Kang Liu, Shuai Wang, and Qiuling Song*, J. Am. Chem. Soc. 2021, 143, 13124-13134.

27. “Difluorocarbene enables to access 2-fluoroindoles from ortho-vinylanilines”, Jianke Su, Xinyuan Hu, Hua Huang, Yu Guo and Qiuling Song*, Nat. Commun. 2021, 12, 4986-4996.

26. “Construction of Axially Chiral Arylborons via Atroposelective Miyaura Borylation”, Kai Yang, Yanfei Mao, Jie Xu, Hao Wang, Yong He, Wangyang Li and Qiuling Song*, J. Am. Chem. Soc. 2021, 143, 10048–10053.

25. “Tetracoordinate Boron Intermediates Enabled Unconventional Transformations”, Kai Yang and Qiuling Song*, Acc. Chem. Res.,2021, 54, 2298–2312.

24. “Elemental sulfur enabled divergent synthesis of disulfides, diselenides and polythiophenes from β-CF3-1,3-enynes”, Shengnan Jin, Shi-Jun L, Xingxing Ma, Jianke Su, Haohua Chen, Yu Lan* and Qiuling Song*, Angew. Chem. Int. Ed. 2021, 60, 881-888.

23. “Recent Progress on Selective Deconstructive Modes of Halodifluoromethyl and Trifluoromethyl-containing Reagents”, Xingxing Ma and Qiuling Song*, Chem. Soc. Rev., 2020, 49, 9197-9219.

22. “Cu-catalyzed regio- and stereodivergent chemoselective sp2/sp3 1,3-and 1,4-diborylations of CF3-containing 1,3-enynes”, Zhijie Kuang, Haohua Chen, Jian Qiu, Zongliang Ou, Yu Lan* and Qiuling Song*, Chem, 2020, 6, 2347-2363.

21. “Deconstructive Functionalizations of Unstrained Carbon−Nitrogen Cleavage Enabled by Difluorocarbene”, Jianke Su, Xingxing Ma, Zongliang Ou, Qiuling Song*, ACS Cent. Sci. 2020, 6, 1819-1826.

20. “Passerini-Type Reaction of Boronic Acids Enables α-Hydroxyketones”, Kai Yang, Feng Zhang, Tongchang Fang, Chaokun Li, Wangyang Li, and Qiuling Song*, Nat. Commun. 2020, 12, 441-450.

19. “Design, Synthesis, and Applications of ortho-Sulfur Substituted Arylphosphanes”, Yu Guo, Ying Luo, Shiqiang Mu, Jianke Su, Jian Xu and Qiuling Song*, CCS Chem. 2022, DOI:10.31635/ccschem.022.202201944.

18. “Deconstructive Difunctionalizations of Carbon-Oxygen Cleavage in Cyclic Ethers Enabled by Difluorocarbene to Access Difluoromethyl Ethers”, Heyun Sheng, Jianke Su, Xue Li and Qiuling Song*, CCS Chem. 2022, DOI: 10.31635/ccschem.022.202101576.

17. “Atom Recombination of Difluorocarbene Enables 3-Fluorinated Oxindoles from 2-Aminoarylketones”. Guan Zhang , Qianqian Shi , Mengyuan Hou , Kai Yang , Shihui Wang , Shuai Wang , Wangyang Li , Chaokun Li , Jian Qiu , Hetao Xu , Lu Zhou , Cece Wang , Shi-Jun Li , Yu Lan* , and Qiuling Song*, CCS Chemistry. 2021, 3, 1613–1621.

16. “Catalytic Atroposelective Catellani Reaction Enables to Construct Axially Chiral Biaryl Monophosphine Oxides”, Qiang Feng, Xingxing Ma, Wen Bao, Shi-Jun Li, Yu Lan*, and Qiuling Song*, CCS Chemistry. 2021, 3, 377-387.

15. “Palladium-catalyzed Three-component Synthesis of Phosphine-containing Tetrasubstituted Acyclic Unsymmetric Allcarbon Olefins”, Xingxing Ma, Puhui Li, Jinchao Liang, Hejun An, Kai Yang, and Qiuling Song *, Cell Rep. Phy. Sci. 2020, 2, 100629-100641.

14. “Transition-Metal-Free Double Insertive Coupling of Isocyanides with Arylboronic Acids Enabled Diarylmethanamines”, Kai Yang, Xiaoxiao Hu, Wangyang Li, Jian Qiu, Qiang Feng, Shihui Wang, Guan Zhang, Zhijie Kuang, Peiyuan Yu* and Qiuling Song*, Cell Rep. Phy. Sci. 2020, 1, 100268-100283.

13. “Palladium-catalyzed Suzuki-Miyaura coupling of thioureas or thioamides”, Shaoyu Mai, Wendong Li, Xue Li, Yingwei Zhao, Qiuling Song*, Nat. Commun. 2019, 10, 5709-5731.

12. “Michael Reaction Inspired Atroposelective Construction of Axially Chiral Biaryls”, Shengyi Yan, Wang Xia, Shaoyu Li, Qiuling Song*, Shaohua Xiang, Bin Tan*, J. Am. Chem. Soc. 2020, 142, 7322-7327.

11. “Chiral Brønsted Acid from Chiral Phosphoric Acid Boron Complex and Water: Asymmetric Reduction of Indoles” Kai Yang, Yixian Lou, Chenglan Wang, Liang-Wen Qi, Tongchang Fang, Feng Zhang, Hetao Xu, Lu Zhou, Wangyang Li, Guan Zhang, Peiyuan, Yu*, Qiuling Song*, Angew. Chem. Int. Ed. 2020, 59, 3294-3299.

10. “Stereospecific 1,4-Metallate Shift Enables Stereoconvergent Synthesis of Ketoximes”, Kai Yang, Feng Zhang, Tongchang Fang, Guan Zhang, Qiuling Song*, Angew. Chem. Int. Ed.  2019, 58, 13421-13426.

9. “Divergent Synthesis of Disulfanes and Benzenesulfonothioates Bearing 2-Aminofurans From N-Tosylhydrazone-Bearing Thiocarbamates”, Shaoyu Mai and Qiuling Song*, Angew. Chem. Int. Ed. 2017, 56, 7952-7957.

8. “Radical-Induced 1,2-Boron Shift, Enabling 1,3-Difunctionalization of Allylboronic Esters”, Kai Yang,  Zhijie Kuang, Qiuling Song*, Chem  2020, 6, 330-331.

7. “Design and Applications of Highly Stereoselective 1, 3-Dienes Aldehydes or Ketones”, Qiang Feng, Shihui Wang, Xingxing Ma, Changqing Rao and Qiuling Song*, Sci. China. Chem. 2022, doi:10.1007/s11426-021-1204-5.

6. “C-F bond activation under transition-metal-free conditions”, Han-Jun Ai, Xingxing Ma, Qiuling Song and Xiao-Feng Wu*, Sci. China Chem. 2021, 64, 1630-1659.

5. “Base-catalyzed Diborylation of Alkynes: Synthesis and Applications of cis-1,2-Bis(boryl)alkenes”, Zhijie Kuang, Guoliang Gao and Qiuling Song*, Sci. China Chem. 2020, 62, 62-66.

4. “Base-Catalyzed Highly Diastereoselective Deuteration of Diarylethynes via Domino-Borylation-Protodeboronation”, Zhijie Kuang, Shaoyu Mai, Kai Yang and Qiuling Song*, Sci. Bull., 2019, 22, 1685-1690.

3. “Enantio- and Diastereoselective Diarylmethylation of 1,3-Dicarbonyl Compounds”, Xin Li, Songtao He and Qiuling Song*, Chem. Sci. 2020, 11, 5969-5973.

2. “S8-Catalyzed Triple Cleavage of Bromodifluoro Compounds for the Assembly of N-containing Heterocycles”, Shuilin Deng, Haohua Chen, Xingxing Ma, Yao Zhou, Kai Yang, Yu Lan*, and Qiuling Song*, Chem. Sci. 2019, 10, 6828-6833.

1. “Four-Coordinate Triarylborane Synthesis via Cascade B-Cl/C-B Cross-Metathesis and C-H Bond Borylation”, Kai Yang, Guan Zhang and Qiuling Song*, Chem. Sci. 2018, 9,7666-7672.

获奖情况：

曾入选福建百人计划；荣获2015年福建省五四青年奖章、2016年度第六届中国侨界贡献奖（创新人才）、2018 ACP Lectureship Awards (Singapore and Japan)、2019 ACP Lectureship Awards (Taiwan and Korea) 、2021年Thieme Chemistry Journal Awards（2021），以及药明康德生命化学研究奖（2022）等；2021年当选英国皇家化学学会会士。

社会兼职：

目前担任Organic letters 的编委、Journal of Heterocyclic Chemistry和Green Synthesis & Catalysis的副主编，担任《中国化学快报》(Chinese Chemical Letters)、《化学学报》和《中国医药工业杂志》的编委，以及《有机化学》(Chinese Journal of Organic Chemistry)青年编委。

其他：

诚招硕士研究生、博士研究生、研究助理、博士后。